Distinct effects of individual opioids on the morphology of spines depend upon the internalization of mu opioid receptors.

@article{Liao2007DistinctEO,
  title={Distinct effects of individual opioids on the morphology of spines depend upon the internalization of mu opioid receptors.},
  author={Dezhi Liao and Olga O. Grigoriants and Wei Wang and Katie M. Wiens and Horace H. Loh and P C Law},
  journal={Molecular and cellular neurosciences},
  year={2007},
  volume={35 3},
  pages={456-69}
}
This study has examined the relationship between the effects of opioids on the internalization of mu opioid receptors (MORs) and the morphology of dendritic spines. Several opioids (morphine, etorphine, DAMGO or methadone) were applied to cultured hippocampal neurons. Live imaging and biochemical techniques were used to examine the dynamic changes in MOR… CONTINUE READING