Distinct contributions of CXCR4b and CXCR7/RDC1 receptor systems in regulation of PGC migration revealed by medaka mutants kazura and yanagi.

@article{Sasado2008DistinctCO,
  title={Distinct contributions of CXCR4b and CXCR7/RDC1 receptor systems in regulation of PGC migration revealed by medaka mutants kazura and yanagi.},
  author={Takao Sasado and Akihito Yasuoka and Keiko Abe and Hiroshi Mitani and Makoto Furutani-Seiki and Minoru Tanaka and Hisato Kondoh},
  journal={Developmental biology},
  year={2008},
  volume={320 2},
  pages={328-39}
}
Migratory pathways of PGCs to the gonad vary depending on the vertebrate species, yet the underlying regulatory mechanisms guiding PGCs are believed to be largely common. In teleost medaka embryo, PGC migration follows two major steps before colonizing in gonadal areas: (1) bilateral lineup in the trunk and (2) posterior drift of PGCs. kazura (kaz) and… CONTINUE READING