Distinct clinical characteristics of myeloproliferative neoplasms with calreticulin mutations.


Somatic insertions/deletions in the calreticulin gene have recently been discovered to be causative alterations in myeloproliferative neoplasms. A combination of qualitative and quantitative allele-specific polymerase chain reaction, fragment-sizing, high resolution melting and Sanger-sequencing was applied for the detection of three driver mutations (in… (More)
DOI: 10.3324/haematol.2014.107482


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