Distinct claudin expression profile in histologic subtypes of lung cancer.

  title={Distinct claudin expression profile in histologic subtypes of lung cancer.},
  author={Judit Moldvay and M{\'a}rta J{\"a}ckel and Csilla P{\'a}ska and Ibolya Solt{\'e}sz and Zsuzsa Schaff and Andr{\'a}s Kiss},
  journal={Lung cancer},
  volume={57 2},
PURPOSE Claudins are the main constituents of tight junctions. Little is known about their expression and localization in the normal bronchial epithelium and in lung cancer. PATIENTS AND METHODS One hundred four lung cancer tissue blocks were studied including 46 adenocarcinomas (ADC), 30 squamous cell carcinomas (SCC), 15 small cell lung cancers (SCLC), 8 typical and 5 atypical carcinoids. All slides contained normal bronchial mucosa as well. Immunohistochemistry using antibodies against… CONTINUE READING
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