Distinct classes of yeast promoters revealed by differential TAF recruitment.

@article{Li2000DistinctCO,
  title={Distinct classes of yeast promoters revealed by differential TAF recruitment.},
  author={Xiangen Li and Sukesh R Bhaumik and Michael R. Green},
  journal={Science},
  year={2000},
  volume={288 5469},
  pages={1242-4}
}
The transcription factor TFIID contains the TATA box binding protein (TBP) and multiple TBP-associated factors (TAFs). Here, the association of TFIID components with promoters that either are dependent on multiple TAFs (TAFdep) or have no apparent TAF requirement (TAFind) is analyzed in yeast. At TAFdep promoters, TAFs are present at levels comparable to that of TBP, whereas at TAFind promoters, TAFs are present at levels that approximate background. After inactivation of several general… CONTINUE READING
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