Distinct centromere domain structures with separate functions demonstrated in live fission yeast cells.

@article{Appelgren2003DistinctCD,
  title={Distinct centromere domain structures with separate functions demonstrated in live fission yeast cells.},
  author={Henrik Appelgren and Barbara Kniola and Karl Ekwall},
  journal={Journal of cell science},
  year={2003},
  volume={116 Pt 19},
  pages={4035-42}
}
Fission yeast (Saccharomyces pombe) centromere DNA is organized in a central core region flanked on either side by a region of outer repeat (otr) sequences. The otr region is known to be heterochromatic and bound by the Swi6 protein whereas the central core region contains an unusual chromatin structure involving the histone H3 variant Cnp1 (S. pombe CENP-A). The central core is the base for formation of the kinetochore structure whereas the flanking region is important for sister centromere… CONTINUE READING
25 Citations
39 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 25 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 39 references

Similar Papers

Loading similar papers…