Distinct cellular expression of calcineurin A alpha and A beta in rat brain.

@article{Kuno1992DistinctCE,
  title={Distinct cellular expression of calcineurin A alpha and A beta in rat brain.},
  author={T AKAFUMI Kuno and Hideyuki Mukai and Akio Ito and Chiung Dan Chang and Koichiro Kishima and Naoaki Saito and Chie Tanaka},
  journal={Journal of neurochemistry},
  year={1992},
  volume={58 5},
  pages={1643-51}
}
Specific polyclonal antibodies that distinguish the two distinct isoforms of the catalytic subunit of calmodulin-dependent protein phosphatase, calcineurin A alpha and A beta, were prepared, and the distribution of calcineurin A alpha and A beta in rat brain was studied using immunochemical and immunocytochemical techniques. Immunochemical measurement revealed that the regional distributions of the two isoforms differed and that A alpha was more abundant than A beta in the rat brain. The… CONTINUE READING

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