Distinct cellular and molecular mechanisms for β3 adrenergic receptor-induced beige adipocyte formation

@inproceedings{Jiang2017DistinctCA,
  title={Distinct cellular and molecular mechanisms for β3 adrenergic receptor-induced beige adipocyte formation},
  author={Yuwei Jiang and Daniel C Berry and Jonathan M. Graff},
  booktitle={eLife},
  year={2017}
}
Beige/brite adipocytes are induced within white adipose tissues (WAT) and, when activated, consume glucose and fatty acids to produce heat. Classically, two stimuli have been used to trigger a beiging response: cold temperatures and β3-adrenergic receptor (Adrb3) agonists. These two beiging triggers have been used interchangeably but whether these two stimuli may induce beiging differently at cellular and molecular levels remains unclear. Here, we found that cold-induced beige adipocyte… CONTINUE READING

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