Distinct biochemical requirements for the budding, targeting, and fusion of ER-derived transport vesicles

@article{Rexach1991DistinctBR,
  title={Distinct biochemical requirements for the budding, targeting, and fusion of ER-derived transport vesicles},
  author={Michael F. Rexach and Randy Schekman},
  journal={The Journal of Cell Biology},
  year={1991},
  volume={114},
  pages={219 - 229}
}
The transport of pro-alpha-factor from the ER to the Golgi apparatus in gently lysed yeast spheroplasts is mediated by diffusible vesicles. These transport vesicles contain core-glycosylated pro-alpha-factor and are physically separable from donor ER and target Golgi compartments. The formation of diffusible vesicles from the ER requires ATP, Sec12p, Sec23p, and GTP hydrolysis. The vesicles produced are functionally distinct from the ER: they transfer pro-alpha-factor to the Golgi apparatus… CONTINUE READING
Highly Influential
This paper has highly influenced 12 other papers. REVIEW HIGHLY INFLUENTIAL CITATIONS