Distinct Roles for Secreted Semaphorin Signaling in Spinal Motor Axon Guidance


Neuropilins, secreted semaphorin coreceptors, are expressed in discrete populations of spinal motor neurons, suggesting they provide critical guidance information for the establishment of functional motor circuitry. We show here that motor axon growth and guidance are impaired in the absence of Sema3A-Npn-1 signaling. Motor axons enter the limb precociously… (More)
DOI: 10.1016/j.neuron.2006.01.002


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