Distinct Roles for Dectin-1 and TLR4 in the Pathogenesis of Aspergillus fumigatus Keratitis

Abstract

Aspergillus species are a major worldwide cause of corneal ulcers, resulting in visual impairment and blindness in immunocompetent individuals. To enhance our understanding of the pathogenesis of Aspergillus keratitis, we developed a murine model in which red fluorescent protein (RFP)-expressing A. fumigatus (Af293.1RFP) conidia are injected into the… (More)
DOI: 10.1371/journal.ppat.1000976

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Cite this paper

@inproceedings{Leal2010DistinctRF, title={Distinct Roles for Dectin-1 and TLR4 in the Pathogenesis of Aspergillus fumigatus Keratitis}, author={Sixto Manuel Leal and Susan Cowden and Yen-Cheng Hsia and Mahmoud Afif Ghannoum and Michelle Momany and Eric Pearlman}, booktitle={PLoS pathogens}, year={2010} }