Distinct Oral Neutrophil Subsets Define Health and Periodontal Disease States.

@article{Fine2016DistinctON,
  title={Distinct Oral Neutrophil Subsets Define Health and Periodontal Disease States.},
  author={Noah Fine and Siavash Hassanpour and Alon Borenstein and Corneliu Sima and Morvarid Oveisi and James W. Scholey and David Zi Cherney and Michael Glogauer},
  journal={Journal of dental research},
  year={2016},
  volume={95 8},
  pages={
          931-8
        }
}
Neutrophils exit the vasculature and swarm to sites of inflammation and infection. However, these cells are abundant in the healthy, inflammation-free human oral environment, suggesting a unique immune surveillance role within the periodontium. We hypothesize that neutrophils in the healthy oral cavity occur in an intermediary parainflammatory state that allows them to interact with and contain the oral microflora without eliciting a marked inflammatory response. Based on a high-throughput… CONTINUE READING

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