Distinct Neural Circuits for the Formation and Retrieval of Episodic Memories

  title={Distinct Neural Circuits for the Formation and Retrieval of Episodic Memories},
  author={Dheeraj S Roy and Takashi Kitamura and Teruhiro Okuyama and Sachie K Ogawa and C. Sun and Yuichi Obata and Atsushi Yoshiki and Susumu Tonegawa},
The formation and retrieval of a memory is thought to be accomplished by activation and reactivation, respectively, of the memory-holding cells (engram cells) by a common set of neural circuits, but this hypothesis has not been established. The medial temporal-lobe system is essential for the formation and retrieval of episodic memory for which individual hippocampal subfields and entorhinal cortex layers contribute by carrying out specific functions. One subfield whose function is poorly known… CONTINUE READING
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