Distinct Mitral Valve Proteomic Profiles in Rheumatic Heart Disease and Myxomatous Degeneration

@inproceedings{Martins2014DistinctMV,
  title={Distinct Mitral Valve Proteomic Profiles in Rheumatic Heart Disease and Myxomatous Degeneration},
  author={Carlo de Oliveira Martins and Keity Souza Santos and Frederico Moraes Ferreira and Priscila Camillo Teixeira and Pablo Maria Alberto Pomerantzeff and Carlos MA Brand{\~a}o and Roney Orismar Sampaio and Guilherme Sobreira Spina and Jorge Kalil and Luiza Guilherme and Edecio Cunha-Neto},
  booktitle={Clinical Medicine Insights. Cardiology},
  year={2014}
}
Rheumatic heart disease (RHD) affects heart-valve tissue and is the most serious consequence of group A Streptococcus infection. Myxomatous degeneration (MXD) is the most frequent valvopathy in the western world. In the present work, key protein expression alterations in the heart-valve tissue of RHD and MXD patients were identified and characterized, with controls from cadaveric organ donors. Proteins were separated by two-dimensional (2D)-electrophoresis and identified by mass spectrometry… CONTINUE READING

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