Distinct HLA class II alleles influence antibody response to the Plasmodium vivax Duffy binding protein


Plasmodium vivax infects human reticulocytes through a major pathway that requires interaction between an apical parasite protein, the Duffy binding protein (region II, DBPII) and its cognate receptor on reticulocytes, the Duffy antigen receptor for chemokines (DARC). Although most people naturally exposed to P. vivax fail to develop antibodies that inhibit… (More)
DOI: 10.1186/1475-2875-13-S1-P51