Distinct Effects of Tetragastrin in Rat Gastroduodenal Mucosa on Mucin Content and Mucosal Protective Action Against Histamine-Induced Injury

Abstract

We examined the effects of tetragastrin on mucin(mucus glycoprotein) content and mucosal damage in therat stomach and duodenum. Following an injection oftetragastrin (12, 120, or 400 μg/kg subcutaneously), no macroscopic damage was found to the gastricmucosa but an increase in corpus mucin content wasnoted, whereas mucosal lesions appeared and the… (More)
DOI: 10.1023/A:1018839003603

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