Distinct DNase-I hypersensitive sites are associated with TAL-1 transcription in erythroid and T-cell lines.

Abstract

The tal-1 gene, frequently activated in human T-cell acute lymphoblastic leukemia (T-ALL), is expressed in the erythroid, megakaryocytic, and mast cell lineages during normal hematopoiesis. To gain further insight into the molecular mechanisms that control tal-1 expression, we investigated tal-1 chromatin structure in erythroid/megakaryocytic cell lines and… (More)

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@article{LeroyViard1994DistinctDH, title={Distinct DNase-I hypersensitive sites are associated with TAL-1 transcription in erythroid and T-cell lines.}, author={K Leroy-Viard and M A Vinit and Nathalie Lecointe and Dani{\`e}le Mathieu-Mahul and P. H. Romeo}, journal={Blood}, year={1994}, volume={84 11}, pages={3819-27} }