Distinct Contributions of Dopamine in the Dorsolateral Striatum and Nucleus Accumbens Shell to the Reinforcing Properties of Cocaine

@article{Veeneman2012DistinctCO,
  title={Distinct Contributions of Dopamine in the Dorsolateral Striatum and Nucleus Accumbens Shell to the Reinforcing Properties of Cocaine},
  author={Maartje M J Veeneman and Mark H. Broekhoven and Ruth Damsteegt and Louk J.M.J. Vanderschuren},
  journal={Neuropsychopharmacology},
  year={2012},
  volume={37},
  pages={487-498}
}
Dopaminergic neurotransmission in the dorsal and ventral striatum is thought to be involved in distinct aspects of cocaine addiction. Ventral striatal dopamine mediates the acute reinforcing properties of cocaine, whereas dopamine in the dorsolateral striatum (DLS) is thought to become involved in later stages of the addiction process to mediate well-established cue-controlled drug seeking. However, it is unclear whether the DLS also has a role in the reinforcing properties of cocaine itself… 
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