Distinct Acyl Protein Transferases and Thioesterases Control Surface Expression of Calcium-activated Potassium Channels*

@inproceedings{Tian2012DistinctAP,
  title={Distinct Acyl Protein Transferases and Thioesterases Control Surface Expression of Calcium-activated Potassium Channels*},
  author={Lijun Tian and Heather McClafferty and H G Knaus and Peter J. van Ruth and Michael J Shipston},
  booktitle={The Journal of biological chemistry},
  year={2012}
}
Protein palmitoylation is rapidly emerging as an important determinant in the regulation of ion channels, including large conductance calcium-activated potassium (BK) channels. However, the enzymes that control channel palmitoylation are largely unknown. Indeed, although palmitoylation is the only reversible lipid modification of proteins, acyl thioesterases that control ion channel depalmitoylation have not been identified. Here, we demonstrate that palmitoylation of the intracellular S0-S1… CONTINUE READING

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2010)Mutational analysis of Saccharomyces cerevisiae Erf2 reveals a two BK Channel Regulation by Acyl Transferases and Thioesterases 14724 JOURNAL OF BIOLOGICAL CHEMISTRY VOLUME

  • D. A. Mitchell, G. Mitchell, Y. Ling, C. Budde, R. J. Deschenes
  • APRIL 27,
  • 2012

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