Corpus ID: 214693252

Distant sequence similarity between hepcidin and the novel coronavirus spike glycoprotein: a potential hint at the possibility of local iron dysregulation in COVID-19.

@article{Ehsani2020DistantSS,
  title={Distant sequence similarity between hepcidin and the novel coronavirus spike glycoprotein: a potential hint at the possibility of local iron dysregulation in COVID-19.},
  author={Sepehr Ehsani},
  journal={arXiv: Biomolecules},
  year={2020}
}
  • Sepehr Ehsani
  • Published 2020
  • Chemistry, Biology
  • arXiv: Biomolecules
  • The spike glycoprotein of the SARS-CoV-2 virus, which causes COVID-19, has attracted attention for its vaccine potential and binding capacity to host cell surface receptors. Much of this research focus has centered on the ectodomain of the spike protein. The ectodomain is anchored to a transmembrane region, followed by a cytoplasmic tail. Here we report a distant sequence similarity between the cysteine-rich cytoplasmic tail of the coronavirus spike protein and the hepcidin protein that is… CONTINUE READING

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