Distance in cancer gene expression from stem cells predicts patient survival

Abstract

The degree of histologic cellular differentiation of a cancer has been associated with prognosis but is subjectively assessed. We hypothesized that information about tumor differentiation of individual cancers could be derived objectively from cancer gene expression data, and would allow creation of a cancer phylogenetic framework that would correlate with… (More)
DOI: 10.1371/journal.pone.0173589

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