Distal site of action of parathyroid hormone on phosphate reabsorption.

  title={Distal site of action of parathyroid hormone on phosphate reabsorption.},
  author={Franklyn G. Knox and Claude P. Lechene},
  journal={The American journal of physiology},
  volume={229 6},
The sites of inhibited phosphate transport following administration of bovine parathyroid hormone (bPTH) to thyroparathyroidectomized (TPTX) dogs were investigated. Phosphate reabsorption by the proximal and distal nephron was studied using recollection micropuncture, stop-flow methodology, and electron-probe microanalysis. Following bPTH, delivery of phosphate from the proximal tubule increased from 26 to 37% of the filtered load, P less than .01. Fractional phosphate excretion increased from… CONTINUE READING

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