Distal lung dysfunction at night in nocturnal asthma.

  title={Distal lung dysfunction at night in nocturnal asthma.},
  author={Monica Kraft and Juno Pak and Richard J. Martin and David Kaminsky and Charles G. Irvin},
  journal={American journal of respiratory and critical care medicine},
  volume={163 7},
We have previously shown that patients with nocturnal worsening of asthma (nocturnal asthma) exhibit increased parenchymal inflammation at night. To evaluate the functional significance of this parenchymal inflammation, 10 subjects with nocturnal asthma (NA), four subjects with non-nocturnal asthma (NNA), and four normal control subjects underwent bronchoscopy with measurement of peripheral airways resistance (Rp) at 4:00 P.M. and at 4:00 A.M. Employing a wedged bronchoscope technique, Rp was… CONTINUE READING

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