Dissolving microneedle patch for transdermal delivery of human growth hormone.

@article{Lee2011DissolvingMP,
  title={Dissolving microneedle patch for transdermal delivery of human growth hormone.},
  author={Jeong Woo Lee and Seong-O Choi and Eric I. Felner and Mark R. Prausnitz},
  journal={Small},
  year={2011},
  volume={7 4},
  pages={531-9}
}
The clinical impact of biotechnology has been constrained by the limitations of traditional hypodermic injection of biopharmaceuticals. Microneedle patches have been proposed as a minimally invasive alternative. In this study, the translation of a dissolving microneedle patch designed for simple, painless self-administration of biopharmacetucials that generates no sharp biohazardous waste is assessed. To study the pharmacokinetics and safety of this approach, human growth hormone (hGH) was… CONTINUE READING

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