Dissolution properties of control released solid dispersion of carvedilol with HPMC and Eudragit RS

@article{Shim2012DissolutionPO,
  title={Dissolution properties of control released solid dispersion of carvedilol with HPMC and Eudragit RS},
  author={Jung Bo Shim and Min Jeong Kim and Seul Ji Kim and Su Ji Kang and Ji Hye Lee and Hyeong Seok Kim and Dongwon Lee and Gilson Khang},
  journal={Journal of Pharmaceutical Investigation},
  year={2012},
  volume={42},
  pages={285-291}
}
In this study, solid dispersion for carvedilol was prepared by using spray-drying method. Solid dispersions were formulated with carvedilol and Eudragit RS and hydroxypropyl methylcellulose to control the dissolution rates of carvedilol. Scanning electron microscope was used to analyze surface of solid dispersion samples. Differential scanning calorimetry and powder X-ray diffraction were used to analyze the crystallinity of solid dispersions. Fourier transform infrared spectroscopy was used to… CONTINUE READING
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