Dissolution behavior of β-cyclodextrin molecular inclusion complexes of aceclofenac

@inproceedings{Dua2011DissolutionBO,
  title={Dissolution behavior of β-cyclodextrin molecular inclusion complexes of aceclofenac},
  author={Kamal Kumar Dua and Kavita Pabreja and Malipeddi Venkata Ramana and Vinny Lather},
  booktitle={Journal of pharmacy & bioallied sciences},
  year={2011}
}
The objective of the present investigation was to study the effect of β-cyclodextrin (β-CD) on the in vitro dissolution of aceclofenac (AF) from molecular inclusion complexes. Aceclofenac molecular inclusion complexes in 1:1 and 1:2 M ratio were prepared using a kneading method. The in vitro dissolution of pure drug, physical mixtures, and cyclodextrin inclusion complexes was carried out. Molecular inclusion complexes of AF with β-CD showed a considerable increase in the dissolution rate in… CONTINUE READING