Dissolution Profile Evaluation of Solid Pharmaceutical Forms Containing Chloramphenicol Marketed in Brazil

@inproceedings{Ferraz2007DissolutionPE,
  title={Dissolution Profile Evaluation of Solid Pharmaceutical Forms Containing Chloramphenicol Marketed in Brazil},
  author={Humberto Gomes Ferraz and Leticia Norma Carpentieri and Sayuri Watanabe},
  year={2007}
}
The dissolution profile for solid pharmaceutical fo rms containing chloramphenicol 250 mg available in Brazil was determined using a method from the American Pharmac opoeia (United States Pharmacopoeia, 2004) and then compared. Two different methods of dissolution pro file comparison were used: ANOVA, and an independen t model. Differences between the formulations were reflected in the dissolution profiles. The presence of meta stable polymorphs or amorphous forms of chloramphenicol pa mit te… CONTINUE READING