Dissociative mechanism of F-actin thermal denaturation

We have applied differential scanning calorimetry to investigate thermal unfolding of F-actin. It has been shown that the thermal stability of F-actin strongly depends on ADP concentration. The transition temperature, T m, increases with increasing ADP concentration up to 1 mM. The T m value also depends on the concentration of F-actin: it increases by… (More)