Dissociation of thrombin generation and platelet secretion in diabetes mellitus.

Abstract

To determine the relationship between thrombin generation and platelet secretion in vivo in diabetes mellitus, we measured simultaneous plasma beta-thromboglobulin (BTG) and fibrinopeptide A (FPA) in 40 insulin-dependent patients without renal disease, and 20 control subjects of similar age. Log mean plasma BTG and FPA were higher in diabetic patients (32.1… (More)

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