Dissociation of the single-ring chaperonin GroEL by high hydrostatic pressure.

@article{Panda2002DissociationOT,
  title={Dissociation of the single-ring chaperonin GroEL by high hydrostatic pressure.},
  author={Markandeswar Panda and Jesse Ybarra and Paul M. Horowitz},
  journal={Biochemistry},
  year={2002},
  volume={41 42},
  pages={12843-9}
}
We investigated the dissociation of single-ring heptameric GroEL (SR1) by high hydrostatic pressure in the range of 1-2.5 kbar. The kinetics of the dissociation of SR1 in the absence and presence of Mg2+, KCl, and nucleotides were monitored using light scattering. The major aim of this investigation was to understand the role of the double-ring structure of… CONTINUE READING