Dissociation of supraspinal and spinal actions of morphine: a quantitative evaluation.

@article{Barton1980DissociationOS,
  title={Dissociation of supraspinal and spinal actions of morphine: a quantitative evaluation.},
  author={Claire Barton and Allan I. Basbaum and Howard L Fields},
  journal={Brain research},
  year={1980},
  volume={188 2},
  pages={487-98}
}
Opiate suppression of spinal withdrawal reflexes was tested in rats with lesions of several spinal funiculi to determine the relative contribution of supraspinal descending systems. The latency of tail-flick to noxious heat was used to assess "analgesia". The effect of lesions of dorsolateral funiculus (DLF), dorsal columns (DC) and ventral quadrant (VQ… CONTINUE READING