Dissociation of object and spatial visual processing pathways in human extrastriate cortex.

  title={Dissociation of object and spatial visual processing pathways in human extrastriate cortex.},
  author={J. V. Haxby and Cheryl L. Grady and Barry Horwitz and Leslie G. Ungerleider and Mortimer M. Mishkin and Richard E. Carson and Peter Herscovitch and Mark B. Schapiro and Stanley I. Rapoport},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  volume={88 5},
  • J. Haxby, C. Grady, +6 authors S. Rapoport
  • Published 1 March 1991
  • Biology, Medicine
  • Proceedings of the National Academy of Sciences of the United States of America
The existence and neuroanatomical locations of separate extrastriate visual pathways for object recognition and spatial localization were investigated in healthy young men. Regional cerebral blood flow was measured by positron emission tomography and bolus injections of H2(15)O, while subjects performed face matching, dot-location matching, or sensorimotor control tasks. Both visual matching tasks activated lateral occipital cortex. Face discrimination alone activated a region of… 
Dissociation of object and spatial visual processing pathways in
The existence and neuroanatomical locations of separate extrastriate visual pathways for object recognition and spatial localization were investigated in healthy young men. Regional cerebral blood
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Correlations between normalized regional cerebral blood flow values were used to examine functional associations among posterior brain regions for these two pathways in 17 young men during performance of a face matching task and a dot-location matching task to suggest correlational analysis of normalized rCBF can detect functional interactions between components of proposed brain circuits.
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  • S. Lomber
  • Psychology, Biology
    Progress in brain research
  • 2001
The purpose of this review is to: (1) compare and contrast the relative contributions that the four principle regions in cat extrastriate parietal cortex make to a battery of visual tasks which
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Cross-modal activation of visual cortex during depth perception using auditory substitution of vision
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Objects play an important role in guiding spatial attention through a cluttered visual environment. We used event-related functional magnetic resonance imaging (ER-fMRI) to measure brain activity


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Occipital cortex in man: Organization of callosal connections, related myelo‐ and cytoarchitecture, and putative boundaries of functional visual areas
The pattern of callosal afferents in (human) areas 17, 18, and 19 as well as their cortical architecture are described and the position of some visual areas is inferred.
Attentional modulation of neural processing of shape, color, and velocity in humans.
Psychophysical evidence indicated that the sensitivity for discriminating subtle stimulus changes was higher when subjects focused attention on one attribute than when they divided attention among several attributes.
The Relationship between Global and Local Changes in PET Scans
It is shown that the increase in activity due to a cognitive activation is independent of global activity, with the “nuisance” variable as global activity and the activation condition as the categorical independent variable for an analysis of covariance.
Dissociable visual and spatial impairments following right posterior cerebral lesions: Clinical, neuropsychological and anatomical evidence
The clinical, neuropsychological and post-mortem anatomical data are considered in relation to evidence from physiological research of two major cortico-cortical pathways for object-recognition and spatial perception.
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A technique is described for estimating the position of the intercommisural line (AC–PC line) directly from landmarks on positron emission tomographic images, namely the ventral aspects of the anterior and posterior corpus callosum, the thalamus, and occipital pole, which showed minimal vertical and angular displacement when measured on magnetic resonance imaging (MRI) scans.
Comparing Functional (PET) Images: The Assessment of Significant Change
This report describes an approach that may partially resolve the uncertainty in assessing the significance of statistical parametric maps and models the SPM as a stationary stochastic process.
Strategy for the Measurement of Regional Cerebral Blood Flow Using Short-Lived Tracers and Emission Tomography
  • N. Alpert, L. Eriksson, +6 authors J. Taveras
  • Physics, Medicine
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism
  • 1984
A strategy for measurement of regional CBF that rigorously accounts for differing tracer partition coefficients and recirculation is described, and is convenient for use with positron emission tomography.
Plastic transformation of PET images.
A theory and technique are presented that allow nonlinear resampling of positron emission tomography data to remove nonlinear differences in brain shape. The resampling is determined empirically by a