Dissociation of glomerular filtration and renal blood flow in HgCl2-induced acute renal failure.

Abstract

This study evaluates the role of early renal vasoconstriction in the pathogenesis of mercuric chloride (HgCl2)-induced acute renal failure (ARF) in the dog. Within 3 hr after mercury, glomerular filtration rate (GFR), from 45 +/- 4 25 +/- 2 ml/min, and renal blood flow (RBF), from 268 +/- 22 to 161 +/- 19 ml/min, decreased simultaneously. A rise in diuresis… (More)

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@article{Vanholder1982DissociationOG, title={Dissociation of glomerular filtration and renal blood flow in HgCl2-induced acute renal failure.}, author={Raymond Camille Vanholder and Marleen M Praet and Paul Pattyn and I R Leusen and Norbert H. Lameire}, journal={Kidney international}, year={1982}, volume={22 2}, pages={162-70} }