Dissociation of β1- and β2-adrenergic receptor subtypes in the retrieval of cocaine-associated memory

@article{Fitzgerald2016DissociationO,
  title={Dissociation of β1- and β2-adrenergic receptor subtypes in the retrieval of cocaine-associated memory},
  author={Michael K. Fitzgerald and James M. Otis and Devin Mueller},
  journal={Behavioural Brain Research},
  year={2016},
  volume={296},
  pages={94-99}
}
Drug seeking is maintained by encounters with drug-associated cues, and disrupting retrieval of these drug-cue associations would reduce the risk of relapse. Retrieval of cocaine-associated memories is dependent on β-adrenergic receptor (β-AR) activation, and blockade of these receptors induces a persistent retrieval deficit. Whether retrieval of cocaine-associated memory is mediated by a specific β-AR subtype, however, remains unclear. Using a cocaine conditioned place preference (CPP… CONTINUE READING