Dissociation in prefrontal cortex of affective and attentional shifts

@article{Dias1996DissociationIP,
  title={Dissociation in prefrontal cortex of affective and attentional shifts},
  author={Rebecca Dias and Trevor William Robbins and Angela C. Roberts},
  journal={Nature},
  year={1996},
  volume={380},
  pages={69-72}
}
THE prefrontal cortex is implicated in such human characteristics as volition, planning, abstract reasoning and affect1–6. Frontal-lobe damage can cause disinhibition such that the behaviour of a subject is guided by previously acquired responses that are inappropriate to the current situation7–9. Here we demonstrate that disinhibition, or a loss of inhibitory control, can be selective for particular cognitive functions and that different regions of the prefrontal cortex provide inhibitory… Expand
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