Dissociation enzyme effects on the potassium currents of inner hair cells isolated from guinea-pig cochlea.

Abstract

Tetraethylammonium (TEA)-sensitive potassium currents in the cochlear inner hair cells (IHCs) possess the kinetics of fast inactivation. Some enzymes using for IHCs dissociation affect these inactivation kinetics. IHCs were dissociated from guinea-pig cochlea by 1 mg/ml trypsin or 0.25 mg/ml protease VIII, and the properties of the K+ currents were compared… (More)

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@article{Kimitsuki2005DissociationEE, title={Dissociation enzyme effects on the potassium currents of inner hair cells isolated from guinea-pig cochlea.}, author={Takashi Kimitsuki and Mitsuru Ohashi and Yuki Wada and Shinji Fukudome and Shizuo Komune}, journal={Hearing research}, year={2005}, volume={199 1-2}, pages={135-9} }