Dissociation constants and relative efficacies of agonists acting on alpha adrenergic receptors in rabbit aorta.

Abstract

The dissociation constants (KA values) of l-norepinephrine (l-NE) and seven other agonists acting on alpha adrenergic receptors in rabbit aorta strips were determined by analysis of concentration-response data before and after fractional inactivation of receptors with Dibenamine. In experiments to determine KA values, propranolol was added to block… (More)

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