Dissociation by methylamine of insulin release from glucose-induced electrical activity in isolated mouse islets of Langerhans.

Abstract

The effect of methylamine on electrical activity and simultaneously measured insulin release was investigated in single perifused islets of normal mice. Methylamine, (2 mmol/L or 6 mmol/L) failed to affect beta-cell input resistance and only caused a modest and transient inhibition of electrical activity of islets exposed to 11.1 mmol/L glucose. Methylamine… (More)

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