Dissociating pain from its anticipation in the human brain.

@article{Ploghaus1999DissociatingPF,
  title={Dissociating pain from its anticipation in the human brain.},
  author={Alexander Ploghaus and I. Tracey and Joseph S. Gati and Stuart Clare and Ravi S. Menon and Paul M. Matthews and J. Nicholas P. Rawlins},
  journal={Science},
  year={1999},
  volume={284 5422},
  pages={
          1979-81
        }
}
  • Alexander Ploghaus, I. Tracey, +4 authors J. Nicholas P. Rawlins
  • Published in Science 1999
  • Medicine
  • The experience of pain is subjectively different from the fear and anxiety caused by threats of pain. Functional magnetic resonance imaging in healthy humans was applied to dissociate neural activation patterns associated with acute pain and its anticipation. Expectation of pain activated sites within the medial frontal lobe, insular cortex, and cerebellum distinct from, but close to, locations mediating pain experience itself. Anticipation of pain can in its own right cause mood changes and… CONTINUE READING

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    SHOWING 1-2 OF 2 REFERENCES

    Conditioned Reflexes ( Oxford Univ . Press , Oxford , 1927 ) ; O . H . Mowrer

    • L. Y. Qi, R. S. Frackowiak
    • Psychol . Rev .
    • 1991

    Conditioned Reflexes (Oxford

    • I. P. Pavlov
    • Psychol. Rev. 45,
    • 1927
    VIEW 2 EXCERPTS