Dissociable cortico-striatal connectivity abnormalities in major depression in response to monetary gains and penalties

@article{Admon2014DissociableCC,
  title={Dissociable cortico-striatal connectivity abnormalities in major depression in response to monetary gains and penalties},
  author={Roee Admon and Lisa D. H. Nickerson and Daniel G. Dillon and Avram J. Holmes and Ryan Bogdan and P. Kumar and Darin D. Dougherty and Dan V. Iosifescu and David Mischoulon and Maurizio Fava and Diego A. Pizzagalli},
  journal={Psychological Medicine},
  year={2014},
  volume={45},
  pages={121 - 131}
}
Background Individuals with major depressive disorder (MDD) are characterized by maladaptive responses to both positive and negative outcomes, which have been linked to localized abnormal activations in cortical and striatal brain regions. However, the exact neural circuitry implicated in such abnormalities remains largely unexplored. Method In this study 26 unmedicated adults with MDD and 29 matched healthy controls (HCs) completed a monetary incentive delay task during functional magnetic… 
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