Dissimilar effects of D-mannoheptulose on the phosphorylation of alpha- versus beta-D-glucose by either hexokinase or glucokinase.

@article{Zhang2004DissimilarEO,
  title={Dissimilar effects of D-mannoheptulose on the phosphorylation of alpha- versus beta-D-glucose by either hexokinase or glucokinase.},
  author={Ying Zhang and Philippe Courtois and Abdullah Sener and Willy Jean Malaisse},
  journal={International journal of molecular medicine},
  year={2004},
  volume={14 1},
  pages={107-12}
}
D-mannoheptulose inhibits D-glucose phosphorylation by hexokinase isoenzymes. The present study aims at investigating whether the pattern of such an inhibition differs in the case of alpha- versus beta-D-glucose. The phosphorylation of alpha- and beta-D-[U-14C]glucose was measured over 60-min incubation at 4 degrees C in the presence of bovine heart… CONTINUE READING