Dissemination of carbapenemase-producing Enterobacteriaceae harbouring blaNDM or blaIMI in local market foods of Yangon, Myanmar

@article{Sugawara2019DisseminationOC,
  title={Dissemination of carbapenemase-producing Enterobacteriaceae harbouring blaNDM or blaIMI in local market foods of Yangon, Myanmar},
  author={Yo Sugawara and Hideharu Hagiya and Yukihiro Akeda and Mya Mya Aye and Hpoo Pwint Myo Win and Noriko Sakamoto and Rathina Kumar Shanmugakani and Dan Takeuchi and Isao Nishi and Akiko Ueda and Moh Moh Htun and Kazunori Tomono and Shigeyuki Hamada},
  journal={Scientific Reports},
  year={2019},
  volume={9}
}
The spread of carbapenemase-producing Enterobacteriaceae (CPE) poses a serious threat to clinical practice and public health. These bacteria are present both in clinical settings and non-clinical environments. The presence of CPE in food stuffs has been reported, but sporadically so. Here, we screened for CPE in meat, seafood, and vegetable samples from local markets of Yangon, Myanmar. We obtained 27 CPE isolates from 93 food samples and identified 13 as Escherichia coli, six as Klebsiella… 
View on Springer
nature.com
22 Citations
Highly Influential Citations
3
Background Citations
9

22 Citations

Detection of VIM, NDM and OXA-48 producing carbapenem resistant Enterobacterales among clinical isolates in Southern Hungary.

Among applied phenotypic tests in this study the modified carbapenem inactivation method (mCIM) proved to be the most accurate one compared to that of PCR results.

Vegetable-Derived Carbapenemase-Producing High-Risk Klebsiella pneumoniae ST15 and Acinetobacter baumannii ST2 Clones in Japan: Coexistence of blaNDM-1, blaOXA-66, blaOXA-72, and an AbaR4-Like Resistance Island in the Same Sample

Japanese carbapenemase-producing Gram-negative bacteria isolated from vegetables are identified, posing a food safety issue and a public health concern.

Prevalence and Characterization of Extended-Spectrum β-Lactamase- and Carbapenemase-Producing Enterobacterales from Tunisian Seafood

The results might indicate that bacteria from hospital or farm effluents can reach the open sea and contaminate seafood and fish that are living or raised nearby and monitoring the quality of water discharged to the sea and the presence of MDR bacteria in seafood is mandatory to ensure thequality of fishery products.

Spread of Carbapenem-Resistant Klebsiella pneumoniae Clinical Isolates Producing NDM-Type Metallo-β-Lactamase in Myanmar

Plasmid genes encoding NDMs and 16S rRNA methylases have been spreading in K. pneumoniae high-risk clones, and results indicate that IncFII plasmids harboring blaNDM-5 and IncFIB(pQil) plasmid harboring Bla NDM-1 have beenSpread in K.

Community spread and acquisition of clinically relevant Escherichia coli harbouring blaNDM among healthy Japanese residents of Yangon, Myanmar.

The analysis suggested the acquisition of blaNDM-positive E. coli, which are disseminating in a clinical setting and through retail foods, by healthy residents in Yangon, Myanmar, is suggested.

Carbapenemase-Producing Gram-Negative Bacteria from American Crows in the United States

Wild corvids were examined for the presence of carbapenemase-producing Gram-negative bacteria in the United States and 11 Providencia rettgeri isolates harboring blaIMP-27 on the chromosome as a class 2 integron gene cassette within the Tn7 transposon were detected.

High occurrence of carbapenem‐resistant Escherichia coli isolates from healthy rabbits (Oryctolagus cuniculus): first report of blaIMI and blaVIM type genes from livestock in Tunisia

Findings highlight the importance of rabbit production as reservoir of carbapenem‐resistant E. coli and argue the first report of blaVIM and blaIMP genes in livestock in Tunisia.

Emergence of blaIMI-2- and blaIMI-16-Producing Enterobacter asburiae in the Aquaculture Environment of Jiangsu, China

The occurrence of blaIMI-carrying Enterobacter asburiae in aquaculture-related water samples and fish samples highlights the risk of transmission of blo IMI- Carrying strains through the food chain and the need for effective measures to prevent further dissemination.

ESBL- and Carbapenemase-Producing Escherichia coli and Klebsiella pneumoniae among Bivalves from Portuguese Shellfish Production Areas

The occurrence of extended-spectrum β-lactamase and carbapenemase-producing Enterobacteriaceae in bivalves reveals how the marine environment constitutes a reservoir of critical bacterial pathogens, thus potentially representing a risk to human health.

Dominant Carbapenemase-Encoding Plasmids in Clinical Enterobacterales Isolates and Hypervirulent Klebsiella pneumoniae, Singapore

To delete genes/regions in hypervirulent Klebsiella pneumoniae, ≈1,000-bp fragments upstream and downstream of the target were amplified with PCR and assembled in a conditional suicide pR6KmobsacB vector by using NEBuilder HiFi DNA Assembly Master Mix (New England Biolabs).

References

SHOWING 1-10 OF 34 REFERENCES

Spreading Patterns of NDM-Producing Enterobacteriaceae in Clinical and Environmental Settings in Yangon, Myanmar

Three distinct patterns of the dissemination of blaNDM-harboring plasmids among CPE isolates in Myanmar are highlighted, contributing to a better understanding of their molecular epidemiology and dissemination in a setting of endemicity.

First detection of Klebsiella variicola producing OXA-181 carbapenemase in fresh vegetable imported from Asia to Switzerland

The results of this study suggest that the international production and trade of fresh vegetables constitute a possible route for the spread of carbapenemase-producing Enterobacteriaceae.

Enterobacter cloacae Complex Isolates Harboring blaNMC-A or blaIMI-Type Class A Carbapenemase Genes on Novel Chromosomal Integrative Elements and Plasmids

Enterobacter cloacae complex isolates harboring blaNMC-A/IMI-type carbapenemases are relatively rare in Canada, Though mostly found integrated into the chromosome, some variants are located on plasmids that may enhance their mobility potential.

Genetic characterization of blaNDM-harboring plasmids in carbapenem-resistant Escherichia coli from Myanmar

The results indicate circulation of phylogenetically distinct strains of carbapenem-resistant E. coli with various plasmids harboring blaNDM genes in the hospital.

Development of selective medium for IMP-type carbapenemase-producing Enterobacteriaceae in stool specimens

M-ECC medium was determined as the most favourable selective medium for the detection of IMP-type CPE as well as other types of CPE.

Characteristics of Carbapenem-Resistant Enterobacteriaceae in Ready-to-Eat Vegetables in China

The results suggest that both clonal expansion and horizontal transmission of IncX3- or F35:A-:B1-type plasmids may mediate the spread of CRE in ready-to-eat vegetables in China.

Characterization of IMI-1 beta-lactamase, a class A carbapenem-hydrolyzing enzyme from Enterobacter cloacae

In conclusion, IMI-1, a carbapenem-hydrolyzing beta-lactamase inhibited by clavulanic acid, was identified as a group 2f, class A, carbapanem-Hydrolyzed cephalosporinase.

Carbapenemase-Producing Organisms: A Global Scourge.

  • R. BonomoE. Burd L. Westblade
  • Medicine, Biology
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
  • 2018
This review highlights the current understanding of CPOs with emphasis on their epidemiology, detection, treatment, and control and emerging agents, novel antibiotic combinations and treatment regimens offer promise for management of these infections.

Comprehensive Genome Analysis of Carbapenemase-Producing Enterobacter spp.: New Insights into Phylogeny, Population Structure, and Resistance Mechanisms

The data presented here represent the first comprehensive study of phylogenomic interrogation and the relationship between antibiotic resistance and plasmid discrimination among carbapenem-resistant Enterobacter spp.

Characteristics of Extended-Spectrum β-Lactamase-Producing Escherichia coli in Retail Meats and Shrimp at a Local Market in Vietnam.

The findings indicate that retail foods are contaminated with ESBL-producing E. coli in retail foods in a local city in Vietnam, and further monitoring and public health efforts targeting food administration are needed to control the spread of ES BL-producing bacteria in communities.