Disseminated tumor cells and the risk of locoregional recurrence in nonmetastatic breast cancer.

@article{Bidard2009DisseminatedTC,
  title={Disseminated tumor cells and the risk of locoregional recurrence in nonmetastatic breast cancer.},
  author={François-Cl{\'e}ment Bidard and Youlia M. Kirova and Anne Vincent-Salomon and S{\'e}verine Alran and Yann de Rycke and Brigitte Sigal-Zafrani and Xavier X Sastre-Garau and Laurent Mignot and Alain Fourquet and J. Y. Pierga},
  journal={Annals of oncology : official journal of the European Society for Medical Oncology},
  year={2009},
  volume={20 11},
  pages={1836-41}
}
BACKGROUND In early breast cancer patients, bone marrow (BM)-disseminated tumor cells (DTCs) were associated with distant metastasis and locoregional recurrence. Our aim was to determine whether BM DTC detection could be related to specific locoregional dissemination of cancer cells, according to radiotherapy volumes. PATIENTS AND METHODS The relationship between locoregional recurrence-free survival (LRFS) and DTC detection was evaluated according to the various locoregional volumes… CONTINUE READING
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