Disseminated intravascular coagulation associated with Staphylococcus aureus septicemia is mediated by peptidoglycan-induced platelet aggregation.

@article{Kessler1991DisseminatedIC,
  title={Disseminated intravascular coagulation associated with Staphylococcus aureus septicemia is mediated by peptidoglycan-induced platelet aggregation.},
  author={Craig Kessler and Eric Nussbaum and Carmelita U Tuazon},
  journal={The Journal of infectious diseases},
  year={1991},
  volume={164 1},
  pages={101-7}
}
Disseminated intravascular coagulation (DIC) may complicate severe septicemia caused by Staphylococcus aureus. S. aureus can induce spontaneous platelet aggregation in vitro, the rapidity and degree of which correlates with the severity of DIC in patients with sepsis. Purified peptidoglycan from DIC isolates aggregated human platelets in the presence of… CONTINUE READING