Disseminated encephalomyelitis and multiple sclerosis: two different diseases – a critical review

  title={Disseminated encephalomyelitis and multiple sclerosis: two different diseases – a critical review},
  author={Charles M. Poser and Vesna V. Brinar},
  journal={Acta Neurologica Scandinavica},
  • C. Poser, V. Brinar
  • Published 1 October 2007
  • Medicine, Psychology
  • Acta Neurologica Scandinavica
The practice of initiating immunomodulatory treatment immediately after a clinically isolated syndrome (CIS) suggestive of multiple sclerosis (MS) emphasizes the need to distinguish between disseminated encephalomyelitis (DEM) and MS. Their clinical, genetic, imaging, and histopathological characteristics establish that they are distinct disease entities. Acute and recurrent DEM are more common in children, but also occur in adults. DEM is polysymptomatic and includes signs and symptoms rarely… 
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