Disseminated cytomegalovirus infection in Crohn's disease following anti-tumour necrosis factor therapy.

@article{Helbling2002DisseminatedCI,
  title={Disseminated cytomegalovirus infection in Crohn's disease following anti-tumour necrosis factor therapy.},
  author={Daniel Helbling and Thomas Breitbach and Martin F. Krause},
  journal={European journal of gastroenterology & hepatology},
  year={2002},
  volume={14 12},
  pages={1393-5}
}
This case report describes a 63-year-old woman with a 15-year history of Crohn's disease. After a severe relapse with colitis she was treated with immunosuppressive agents, including an increased dosage of corticosteroids, azathioprine and a single dose of infliximab (anti-tumour necrosis factor-alpha). This led to a brief improvement, which was followed by worsening diarrhoea, fever and skin lesions. Biopsies from upper and lower endoscopies and from an ulcerative skin lesion revealed… CONTINUE READING
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