Disseminated "Mycobacterium genavense" infection in patients with AIDS.

  title={Disseminated "Mycobacterium genavense" infection in patients with AIDS.},
  author={Erik C B{\"o}ttger and Andreas Teske and Philip Kirschner and Steven C Bost and Hernan R Chang and V. Kellner Beer and Bernard Hirschel},
  volume={340 8811},
We describe 18 patients with advanced HIV infection, most of whom had a chronic illness characterised by fever, diarrhoea, and massive loss of weight. Biopsy and necropsy samples revealed abundant acid-fast microorganisms in intestines, liver, spleen, lymph nodes, and many other tissues, which did not grow on solid media, although limited growth was observed in liquid blood cultures. Using primers complementary to bacterial 16S rRNA we amplified DNA sequences from tissue and leucocyte extracts… CONTINUE READING
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