Dissection of the target specificity of the RNA-binding protein HOW reveals dpp mRNA as a novel HOW target.


Regulation of RNA metabolism plays a major role in controlling gene expression during developmental processes. The Drosophila RNA-binding protein Held out wing (HOW), regulates an array of developmental processes in embryonic and adult growth. We have characterized the primary sequence and secondary structural requirements for the HOW response element (HRE… (More)

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