Dissection of the mitochondrial import and assembly pathway for human Tom40.

Abstract

Tom40 is the channel-forming subunit of the translocase of the mitochondrial outer membrane (TOM complex), essential for protein import into mitochondria. Tom40 is synthesized in the cytosol and contains information for its mitochondrial targeting and assembly. A number of stable import intermediates have been identified for Tom40 precursors in fungi, the… (More)

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@article{Humphries2005DissectionOT, title={Dissection of the mitochondrial import and assembly pathway for human Tom40.}, author={Adam D Humphries and Illo C A Streimann and Diana Stojanovski and Amelia J. Johnston and Masato Yano and Nicholas J. Hoogenraad and Michael T Ryan}, journal={The Journal of biological chemistry}, year={2005}, volume={280 12}, pages={11535-43} }