Dissection of signaling pathways in fourteen breast cancer cell lines using reverse-phase protein lysate microarray.

@article{Akkiprik2006DissectionOS,
  title={Dissection of signaling pathways in fourteen breast cancer cell lines using reverse-phase protein lysate microarray.},
  author={Mustafa Akkiprik and Daniel Nicorici and David Cogdell and Y J Jia and Andrea Hategan and Ioan Tabus and Olli P. Yli-Harja and Y D and Aysegul Sahin and Wei Zhang},
  journal={Technology in cancer research & treatment},
  year={2006},
  volume={5 6},
  pages={543-51}
}
Signal transduction pathways play a crucial role in breast cancer development, progression, and response to different therapies. A major problem in breast cancer therapy is the heterogeneity among different tumor types and cell lines commonly used in preclinical studies. To characterize the signaling pathways of some of the commonly used breast cancer cell lines and dissect the relationship among a number of pathways and some key genetic and molecular events in breast cancer development, such… CONTINUE READING

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